What is Sulbutiamine?
Sulbutiamine is a synthetic derivative of thiamine that potentiates interesting nootropic benefits with fatigue, memory, mood and focus. Sulbutiamine essentially is thiamine (B1) that is bound together at the thiol group, allowing it to more easily cross the blood-brain barrier and increase the levels of thiamine and thiamine phosphate esters in the brain.
This simple alteration in molecular structure increases liphophilicity and thereby blood brain barrier (BBB) penetration.
How does Sulbutiamine and Thiamine work?
To help understand better the importance of thiamine on the mind, we should first look and see what is rendered by a deficiency. A condition known as beriberi--one that is usually common only to alcoholics and people with poor nutrition--is directly caused by a deficiency in vitamin b1. Moreover, beriberi is mostly seen in areas that depend heavily on rice as a form of nutrition; in fact, the condition was common enough to warrant the discovery of this molecule from a nation that depends on rice (Japan). The effects of beriberi are heavily weighted neurologically, and can result in:
- Difficulty in walking
- Tingling or loss of feeling (sensation) in hands and feet (numbness)
- Loss of muscle function or paralysis of the lower legs
- Mental confusion/speech difficulties
- Involuntary eye movements (nystagmus)
Although, this does not imply that boosting your brain B1 will yield positive benefit, the removal or negative effect becomes obvious, thiamine is doing something neurologic.
Possible Sulbutiamine Benefits
With that said, sulbutiamine has actually been found to have positive benefits, mainly centered around countering central asthenia (mental fatigue). Sulbutiamine has also been shown to potentiate cholinergic effects in the hyppocampus, which is the center of new memory formation. Furthermore, mice studies have illustrated significant results in object recognition and operant conditioning, implying an positive effect on memory and learning. While the effects differ widely, as with any nootropic, the following benefits have been reported from sulbutiamine:
- Reduced mental fatigue
- Increases mental focus
- Increases alertness
- Improves memory
- Reduces stress and anxiety
- Improved erectile function
More Information on Sulbutiamine CapsulesServing Size: 1 Capsule
Servings per Bottle: 100
Amount per serving: Sulbutiamine, 200mg
Sulbutiamine - 100 Capsules / 200mg Reviews
- THIS PRODUCT ROCKS Review by garyedward
Quality Price ValueAfter a careful review of numerous other suppliers, I took a chance with Smart Powders, At first glance their prices seemed to be ( to good to be true)! The delivery was timely, I ordered 20 gm Sulbutiamine and 100 gm of Cordyceps CS-4 powder. Recovering from a head injury I started experimenting with various nootropic compounds ( Noopept Aniracetam Pramaracetam) with noticeable but limited improvements. The Sulbutiamine synergized my current stack. This product provides the cleanest energy rush. The incredible surge to your mood ,creativity and mental output is comparable to pumping Nitrous Oxide into your lawn mower. Luminosity Scores up 50% in two days. Thank You Smart Powders(Posted on )
- forreal Review by distantblue
Price Value Qualitythis product seems to make me smile all day with increased energy.(Posted on )
I gave some to a friend that was a bit in a rut and she has experienced a great increase in her overall mood / happiness.
i also gave some to a friend that that often takes sublingual b-12 and it did not mix well, gave him too much manic energy
I consume 1x 200mg in the am with my food paired with 700mg of choline bitartrate
- Smart Powders Sulbutiamine - 100 caps - 200mg Review by JENNIFER
Quality Value PricePyritinol makes my brain a little manic, so I decided to try this instead, and find I can focus way better, feel awake on little sleep - provided I dose it out evenly and don't just take one am dose. With Aniracetam (small, like 100mg dose) I find I am more creative and alert. It helps a lot at work or even socially. Also, my anxiety is very minimal when I've hit the dosing "sweet spot".(Posted on )