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D-Serine is an amino acid that a huge component formation of memories. It also offers a huge boost cognitive performance as well as memory. D-Serine is a must to add to any current Nootropic stack.
Some interesting studies:
D-serine regulation: a possible therapeutic approach for central nervous diseases and chronic pain.
D-Serine, an endogenous modulator of NMDA receptors has been shown to play a vital role in many neuropsychiatric functions such as learning, memory, nociception and implicated in pathological conditions like schizophrenia and Alzheimer's disease. We propose possible therapeutic approaches for some CNS diseases and chronic pain, targeting the D-serine levels by manipulating its uptake, biosynthesis and metabolism.
D-Serine: a key to synaptic plasticity?
Two discoveries have put D-serine in the spotlight of neuroscience. First, D-serine was detected in brain tissue at high levels. Second, it was found to act on the N-methyl-D-aspartate receptor (NMDAR). This receptor is central to use-dependent synaptic plasticity, the cellular process which is widely believed to underlie learning. The ensuing quest for the mechanisms of D-serine synthesis, release and clearance, as well as for its physiological significance has provided a wealth of experimental evidence implicating D-serine in synaptic plasticity. However some key questions remain unanswered. Which cells release D-serine and upon what stimuli? Is D-serine supply dynamically regulated? What is the fate of released D-serine? Answering these questions appears to be an essential step in our understanding of how NMDARs trigger synaptic plasticity and learning. This review will highlight some recent advances and avenues of enquiry in dynamic D-serine signaling in the mammalian brain with emphasis on neurophysiology.
Effects of low-dose D-serine on recognition and working memory in mice.
CONCLUSIONS: Our results show that treatment with D -serine can improve performance in tasks related to recognition learning and working memory, suggesting that this agent can be useful for the treatment of disorders involving declines in these cognitive domains.
D-Serine 100g Reviews
- Expensive but effective for schizophrenia Review by kjh
Quality Price ValueI decided to try this product as an alternative treatment to sarcosine for schizophrenia and it worked just as well and took effect faster, witihin about 1 hour rather than 2-3 hours for sarcoine. It's expensive but worth the price.(Posted on )